GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:17920587
FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:20299451
Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:26404741
CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium.
PMID:36115835
Quantitative fragmentomics allow affinity mapping of interactomes.
PMID:14702039
Complete sequencing and characterization of 21,243 full-length human cDNAs.
PMID:15851977
Characterization of the Crumbs homolog 2 (CRB2) gene and analysis of its role in retinitis pigmentosa and Leber congenital amaurosis.
PMID:16713951
oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo.
PMID:16885194
Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells.
PMID:20080584
Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.
PMID:20399730
The apical complex couples cell fate and cell survival to cerebral cortical development.
PMID:21262462
Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells.
PMID:22072575
Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice.
PMID:22579223
Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains.
PMID:23001562
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
PMID:24071007
Spatial-temporal expressions of Crumbs and Nagie oko and their interdependence in zebrafish central nervous system during early development.
PMID:25557779
Defects of CRB2 cause steroid-resistant nephrotic syndrome.
PMID:25636444
Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye.
PMID:26496195
Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2.
PMID:27870829
Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation.
PMID:29473663
Long-term clinicopathologic observation in a case of steroid-resistant nephrotic syndrome caused by a novel Crumbs homolog 2 mutation.
PMID:34262913
Key Role for CRB2 in the Maintenance of Apicobasal Polarity in Retinal Pigment Epithelial Cells.
PMID:36477203
Author Correction: Quantitative fragmentomics allow affinity mapping of interactomes.
PMID:38570189
Human CRB1 and CRB2 form homo- and heteromeric protein complexes in the retina.
PMID:40062402
CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes.