PANTHER family review PTHR24055: IBA propagation assessment for sty1
Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic Gene Ontology annotation based on Rhea mapping
Combined Automated Annotation using Multiple IEA Methods
Active nucleocytoplasmic shuttling required for function and regulation of stress-activated kinase Spc1/StyI in fission yeast.
Heat-shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases.
Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway.
Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway.
The serine/threonine kinase Cmk2 is required for oxidative stress response in fission yeast.
The Srk1 protein kinase is a target for the Sty1 stress-activated MAPK in fission yeast.
Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues.
Cytoplasmic localization of Wis1 MAPKK by nuclear export signal is important for nuclear targeting of Spc1/Sty1 MAPK in fission yeast.
Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1.
RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress.
Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6.
Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase.
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Spc1/Sty1 mediates resistance to toxic cations (Na+, Li+, Ca2+), in part by inducing sod2+ via Atf1 and by interacting with the Hal4 kinase.
The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe.
ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Fission yeast mitogen-activated protein kinase Sty1 interacts with translation factors.
Activation of Srk1 by the mitogen-activated protein kinase Sty1/Spc1 precedes its dissociation from the kinase and signals its degradation.
Genome-wide screen of genes required for caffeine tolerance in fission yeast.
Two-component mediated peroxide sensing and signal transduction in fission yeast.
Aurora promotes cell division during recovery from TOR-mediated cell cycle arrest by driving spindle pole body recruitment of Polo.
H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphatase Ptc4.
The fission yeast stress-responsive MAPK pathway promotes meiosis via the phosphorylation of Pol II CTD in response to environmental and feedback cues.
Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
Dynamic regulation of Cdr1 kinase localization and phosphorylation during osmotic stress.
The fission yeast MAPK Spc1 senses perturbations in Cdc25 and Wee1 activities and targets Rad24 to restore this balance.
Modulation of TOR complex 2 signaling by the stress-activated MAPK pathway in fission yeast.
RNA-Binding Protein Rnc1 Regulates Cell Length at Division and Acute Stress Response in Fission Yeast through Negative Feedback Modulation of the Stress-Activated Mitogen-Activated Protein Kinase Pathway.
Fission Yeast Puf2, a Pumilio and FBF Family RNA-Binding Protein, Links Stress Granules to Processing Bodies.
Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels.
The Hsp40 Mas5 Connects Protein Quality Control and the General Stress Response through the Thermo-sensitive Pyp1.
The fission yeast Pin1 peptidyl-prolyl isomerase promotes dissociation of Sty1 MAPK from RNA polymerase II and recruits Ssu72 phosphatase to facilitate oxidative stress induced transcription.
Schizosaccharomyces pombe MAP kinase Sty1 promotes survival of Δppr10 cells with defective mitochondrial protein synthesis.
Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.
Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.
Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe.
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Spc1 is activated by multiple stresses (osmotic, oxidative, high temperature) and promotes expression of stress-survival genes (gpd1, tps1, pyp2).
Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.
The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.
The Mcs4 response regulator coordinately controls the stress-activated Wak1-Wis1-Sty1 MAP kinase pathway and fission yeast cell cycle.
Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade.
Stress-activated protein kinase pathway in cell cycle control of fission yeast.
The Win1 mitotic regulator is a component of the fission yeast stress-activated Sty1 MAPK pathway.
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1.
Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast.
The fission yeast mitotic regulator win1+ encodes an MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarity.
Evidence for a novel MAPKKK-independent pathway controlling the stress activated Sty1/Spc1 MAP kinase in fission yeast.
Regulation of the Mts1-Mts2-dependent ade6-M26 meiotic recombination hot spot and developmental decisions by the Spc1 mitogen-activated protein kinase of fission yeast.