CG13096 (H0RNN8): evidence and ProtNLM claim review

CG13096 is a 681-residue protein containing ribosomal-uL1-like domains associated with ribosome biogenesis proteins. Its architecture suggests an RNA-associated role, but the exact molecular activity, RNA substrate, and localization of this fly product remain unresolved.

Exact input: H0RNN8, 681 residues. The accession was fetched explicitly with the gene-directory alias; no canonical-sequence substitution is made.

Raw emitted predictions: CG13096-predictions-source.json. Source features: CG13096-uniprot.txt, with an exact extraction in CG13096-sequence-evidence.json.

Sequence and domain evidence

These are sequence/domain observations or explicitly named feature predictions, not measurements of biological function. ARBA assertions and ProtNLM-derived UniProt names are not counted as validation.

DR   InterPro; IPR053110; Ribosomal_L1-TF.
DR   InterPro; IPR023674; Ribosomal_uL1-like.
DR   InterPro; IPR028364; Ribosomal_uL1/biogenesis.

ProtNLM claims

The snapshot emits names and location/keyword statements, with no GO or EC prediction for this target. Each actual statement is assessed below; no GO term has been substituted for it. Categories follow the function-prediction rubric, with nonspecific “uncharacterized” names marked UNC because they contain no testable function. CNN records an independently supported existing annotation; it does not assert a particular training-set composition.

Kind Verbatim emitted statement Assessment Evidence and limitation
Name Uncharacterized protein UNC Uncharacterized protein supplies no testable function. Ribosomal-uL1-like architecture narrows the likely biology but does not establish an intrinsic ribosomal-subunit role.
Location Nucleolus (SL-0188) UNC Ribosomal-uL1-like domains occur in ribosome-biogenesis factors and make nucleolar localization plausible. The exact target has no localization experiment or curated GO localization in the retrieved evidence, so nucleolar residence is not established.
Location Nucleus (SL-0191) UNC A nuclear location is compatible with ribosome biogenesis but is not established solely by the uL1-like fold. The exact target needs localization or a well-resolved characterized ortholog inference.

Literature evidence

No target-specific primary finding is used to establish a molecular activity here. The current assessment is bounded by exact-record architecture and the explicitly identified curated inferences.

Annotation decisions

The accession-specific GOA fetch contains no existing annotation rows. The molecular activity remains unresolved; no broad GO root or invented function is added to create apparent coverage.

Research provenance

Genuine external literature research is requested through the repository Falcon wrapper, with perplexity-lite configured as fallback. Provider output is retained separately as CG13096-deep-research-<provider>.md; its source leads are checked against the underlying publications and exact sequence record.