Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping

Electronic Gene Ontology annotations created by ARBA machine learning models

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1

The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor

A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration.

ESCRT-III recognition by VPS4 ATPases

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

Large-scale proteomics and phosphoproteomics of urinary exosomes

Membrane scission by the ESCRT-III complex

Membrane budding and scission by the ESCRT machinery: it's all in the neck.

Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance

The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes.

ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons.

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.

ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation

ESCRT requirements for EIAV budding

ESCRT machinery is required for plasma membrane repair

Structure of cellular ESCRT-III spirals and their relationship to HIV budding

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

ESCRT-III controls nuclear envelope reformation

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

Recruitment Of HIV Virion Budding Machinery

ESCRT Disassembly

MVB Vesicle Formation

VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations

CHMP7 binds CC2D1B

CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex

SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin

VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope

SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.

Deep research report on CHMP2B