hfq (PP_4894, Q88DD3) review notes
- Existing Falcon deep research (
hfq-deep-research-falcon.md) plus cached primary literature.
- Core: Hfq is the RNA-binding component of the Crc/Hfq catabolite repression system
PMID:24803210;
PMID:24803210
- Repression is antagonised by CrcZ/CrcY PMID:27777366,
and Hfq/Crc stabilise CrcZ PMID:27777366
- Translation repression measured directly for the P. aeruginosa ortholog
PMID:34139006
- 2026-10-23 completion pass: added verbatim support to all rows; NEW translation repressor activity (enables),
negative regulation of translation, and carbon catabolite repression; core functions split into the Crc/Hfq
repressor role and the general sRNA chaperone/RNA-stability role.