Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies.
The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP.
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.
The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.
Defining the membrane proteome of NK cells.
Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.
Dynamic protein-protein interaction wiring of the human spliceosome.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.
Molecular architecture of the human U4/U6.U5 tri-snRNP.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
An Atomic Structure of the Human Spliceosome.
Architecture of the human interactome defines protein communities and disease networks.
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Structure of a human catalytic step I spliceosome.
Structure of the human activated spliceosome in three conformational states.
Structure and Conformational Dynamics of the Human Spliceosomal B(act) Complex.
Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
Structures of the human spliceosomes before and after release of the ligated exon.
Mechanism of 5' splice site transfer for human spliceosome activation.
Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy.
Structure of the activated human minor spliceosome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Mechanism of exon ligation by human spliceosome.
Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8.
Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins.
Structure of the human 20S U5 snRNP.
Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Molecular basis for the activation of human spliceosome.
Systematic identification of post-transcriptional regulatory modules.
Multimodal cell maps as a foundation for structural and functional genomics.
The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein.
Formation of AT-AC C complex
Formation of AT-AC B Complex
ATAC spliceosome mediated Lariat formation,5' splice site cleavage
ATAC spliceosome mediated 3' splice site cleavage, exon ligation
Formation of the Spliceosomal B* complex
Formation of the Spliceosomal Pre-B complex
Formation of the Spliceosomal C* complex
Formation of the Spliceosomal B complex
Formation of the Spliceosomal Bact complex
Formation of the Spliceosomal P complex and exon ligation
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new)
Disassembly of the Intron Lariat Spliceosome (new)
Formation of the Spliceosomal C complex containing intron lariat
NS5 interacts with Spliceosome
Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration.
Investigation of the hepatotoxicity of flutamide: pro-survival/apoptotic and necrotic switch in primary rat hepatocytes characterized by metabolic and transcriptomic profiles in microfluidic liver biochips.
Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.
A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast.
An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2.
Protein-RNA interactions in the U5 snRNP of Saccharomyces cerevisiae.
Subcellular - EFTUD2 - The Human Protein Atlas
UniProt record for EFTUD2
EFTUD2 source evidence and access guide
EFTUD2 literal-data evidence replay