"Western blot analysis showed expression of GPC-4 as a heparan sulphate proteoglycan in the human haematopoietic-progenitor cell line TF-1 and normal human bone marrow."

"These results were confirmed by FACS analysis of TF-1 cells."

"GPC-4-positive progenitor cells and stromal cells were enriched from normal human bone marrow by magnetic-cell sorting and analysed by confocal laser-scanning microscopy."

"Using MudPIT (multidimensional protein identification technology) mass spectrometry, we catalogued 491 proteins in the exosome fraction of human parotid saliva."

"interaction with tetraspanins and GPI-anchored proteins is necessary for ILV formation"

"403 different proteins have been identified from the isolated sperm nuclei"

"Wnts are a highly conserved family of lipid-modified glycoproteins that work as morphogens to activate several signaling pathways"

"Architecture of the human interactome defines protein communities and disease networks"

"we also found likely pathogenic variants in candidate genes GPC4 and RAC3, both linked to the Wnt signaling pathway"

"These data support an initial hypothesis that Robinow syndrome results from perturbation of the Wnt/PCP pathway"

"Robinow syndrome results from perturbation of the Wnt/PCP pathway, suggest specific relevant domains of the proteins involved"

"A reference map of the human binary protein interactome"

"Dual proteome-scale networks reveal cell-specific remodeling of the human interactome"

"Multimodal cell maps as a foundation for structural and functional genomics"

"A defining role of GPC4 is as an astrocyte-derived synaptogenic factor. It promotes excitatory synapse maturation by increasing surface clustering of GluA1-containing AMPA receptors via a LRRTM-GPC4-PTPsigma pathway and by inducing neuronal pentraxin-1 (NPTX1) release from axons."

"Like other glypicans, GPC4 modulates extracellular signaling by binding ligands through HS chains and presenting them to receptors, impacting Wnt, Hedgehog, and FGF pathways."