Gene Ontology annotation through association of InterPro records with GO terms

Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/uppS/uppS-uniprot.txt

UniProtKB entry Q88MH6 for Pseudomonas putida KT2440 uppS

UppS synthesizes undecaprenyl diphosphate from FPP and IPP.

"Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP)."
The product supplies bacterial cell-envelope glycan assembly.

"UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide."
Magnesium is a catalytic cofactor.

"Binds 2 magnesium ions per subunit."

PMID:9882662

Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene.

E. coli UppS is purified from the soluble fraction.

"was purified from the soluble fraction of Escherichia coli"