Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of intracellular localizations of expressed fusion proteins in living cells
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation.
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens.
Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy.
Inhibition of LRRK2 kinase activity stimulates macroautophagy.
A proteome-scale map of the human interactome network.
PI(5)P regulates autophagosome biogenesis.
WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.
The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy.
ER-phagy restrains inflammatory responses through its receptor UBAC2.
ATG16L1 complex transfers LC3 from ATG3 to PE
WIPI2 binds ATG12:ATG5:ATG16L
OpenScientist focused adjudication of PIK3C3 pexophagy and peroxisome localization (comparative machinery evidence)
Nix interacts with WIPI2 to induce mitophagy.
OpenScientist assessment of WIPI2 selective autophagy