Use of the ND evidence code for Gene Ontology (GO) terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Functional genomics reveals genes involved in protein secretion and Golgi organization.
Vmp1, Vps13D, and Marf/Mfn2 function in a conserved pathway to regulate mitochondria and ER contact in development and disease.
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Drosophila Vmp1 is Tango5. Endogenous GFP-Vmp1 co-localizes with ER markers, the vmp1 null is lethal, and loss of Vmp1 blocks Atg8a puncta formation and causes Ref2p accumulation.
"GFP-Vmp1 co-localizes with the ER markers Sec61β and SERCA in intestine cells"
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine.
A model for a partnership of lipid transfer proteins and scramblases in membrane expansion and organelle biogenesis.
Tango5__Q9W2S1-uniprot.txt
Tango5 isoform and family placement (re-review 2026-10-21)
PANTHER family and subfamily names
DROME/Tango5__Q9W2S1/Tango5__Q9W2S1-notes.md