D-x-D-x-(T/V) motif scan of Tim50 proteins

Generated by motif_scan.py on 2026-10-12 from live UniProt sequences.

UniProt Organism Protein Length D-x-D-x-(T/V) matches (motif@start)
Q57ZA0 Trypanosoma brucei Tim50 (positive control, outside the IRD clade) 423 DLDET@242, DLDRV@346
Q3ZCQ8 Homo sapiens TIMM50 353 none
Q9D880 Mus musculus Timm50 353 none
Q02776 Saccharomyces cerevisiae TIM50 476 none
O13636 Schizosaccharomyces pombe tim50 452 none
Q9W4V8 Drosophila melanogaster ttm50 428 none
Q9W0S3 Drosophila melanogaster ttm2 409 DNDTT@333
Q9V9P3 Drosophila melanogaster ttm3 343 none
Q22647 Caenorhabditis elegans scpl-4 452 none
Q8VYE2 Arabidopsis thaliana TIM50 376 none

A match is necessary but not sufficient for catalysis; its absence means the canonical
FCP/SCP nucleophile motif is missing.