Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repair.
XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription.
Functional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB protein.
Distinct strategies to make nucleosomal DNA accessible.
Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress.
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome.
The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase.
Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair.
The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells.
Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression.
The cockayne syndrome B protein is essential for neuronal differentiation and neuritogenesis.
Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation.
Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.
Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation.
The C-terminal Region and SUMOylation of Cockayne Syndrome Group B Protein Play Critical Roles in Transcription-coupled Nucleotide Excision Repair.
Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.
ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice.
CSA and CSB play a role in the response to DNA breaks.
The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II.
Structural basis of human transcription-DNA repair coupling.
Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair.
Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB.
p53 modulation of TFIIH-associated nucleotide excision repair activity.
The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH.
Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II.
Cockayne syndrome group B protein enhances elongation by RNA polymerase II.
Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein.
Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells.
B-WICH recruits histone acetyltransferases
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
B-WICH complex binds rDNA promoter
ERCC8 (CSA) binds stalled RNA Pol II
ERCC6 binds stalled RNA Pol II
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II
Assembly of the pre-incision complex in TC-NER
UVSSA:USP7 deubiquitinates ERCC6
ERCC2-facilitated RNA Pol II backtracking in TC-NER
ERCC5 and RPA bind TC-NER site
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
DNA polymerases delta, epsilon or kappa bind the TC-NER site
3' incision by ERCC5 (XPG) in TC-NER
Ligation of newly synthesized repair patch to incised DNA in TC-NER
Recovery of RNA synthesis after TC-NER
ERCC3-facilitated RNA Pol II backtracking in TC-NER
Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9
Recruitment of CSB, G9a, and NuRD to the rRNA promoter
CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.
CSB-PGBD3 Mutations Cause Premature Ovarian Failure.
The nuclear proteome of Trypanosoma brucei.
Rat Model of Cockayne Syndrome Neurological Disease.
Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation.
Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome.