GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000116
Automatic Gene Ontology annotation based on Rhea mapping
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:10564257
The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repair.
PMID:10944529
XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription.
PMID:12560492
Functional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB protein.
PMID:12769854
Distinct strategies to make nucleosomal DNA accessible.
PMID:16107709
Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress.
PMID:16246722
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome.
PMID:16603771
The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.
PMID:17626041
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase.
PMID:22466612
Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair.
PMID:22483866
The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells.
PMID:23555303
Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression.
PMID:24874740
The cockayne syndrome B protein is essential for neuronal differentiation and neuritogenesis.
PMID:25820262
Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation.
PMID:26030138
Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.
PMID:26044184
Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation.
PMID:26620705
The C-terminal Region and SUMOylation of Cockayne Syndrome Group B Protein Play Critical Roles in Transcription-coupled Nucleotide Excision Repair.
PMID:28292928
Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.
PMID:29203878
ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice.
PMID:29545921
CSA and CSB play a role in the response to DNA breaks.
PMID:32355176
The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II.
PMID:34526721
Structural basis of human transcription-DNA repair coupling.
PMID:38316879
Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair.
PMID:38600235
Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB.
PMID:7663514
p53 modulation of TFIIH-associated nucleotide excision repair activity.
PMID:7664335
The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH.
PMID:8999876
Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II.
PMID:9326587
Cockayne syndrome group B protein enhances elongation by RNA polymerase II.
PMID:9565609
Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein.
PMID:9973627
Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells.
Reactome:R-HSA-5250930
B-WICH recruits histone acetyltransferases
Reactome:R-HSA-5250938
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
Reactome:R-HSA-5250947
B-WICH complex binds rDNA promoter
Reactome:R-HSA-6781833
ERCC8 (CSA) binds stalled RNA Pol II
Reactome:R-HSA-6781840
ERCC6 binds stalled RNA Pol II
Reactome:R-HSA-6781867
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II
Reactome:R-HSA-6782004
Assembly of the pre-incision complex in TC-NER
Reactome:R-HSA-6782069
UVSSA:USP7 deubiquitinates ERCC6
Reactome:R-HSA-6782131
ERCC2-facilitated RNA Pol II backtracking in TC-NER
Reactome:R-HSA-6782138
ERCC5 and RPA bind TC-NER site
Reactome:R-HSA-6782141
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
Reactome:R-HSA-6782204
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
Reactome:R-HSA-6782208
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
Reactome:R-HSA-6782211
DNA polymerases delta, epsilon or kappa bind the TC-NER site
Reactome:R-HSA-6782224
3' incision by ERCC5 (XPG) in TC-NER
Reactome:R-HSA-6782227
Ligation of newly synthesized repair patch to incised DNA in TC-NER
Reactome:R-HSA-6782234
Recovery of RNA synthesis after TC-NER
Reactome:R-HSA-9684118
ERCC3-facilitated RNA Pol II backtracking in TC-NER
Reactome:R-NUL-573373
Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9
Reactome:R-NUL-573385
Recruitment of CSB, G9a, and NuRD to the rRNA promoter
PMID:22032989
CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.
PMID:26218421
CSB-PGBD3 Mutations Cause Premature Ovarian Failure.
PMID:28727848
The nuclear proteome of Trypanosoma brucei.
PMID:31644904
Rat Model of Cockayne Syndrome Neurological Disease.
PMID:31970402
Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation.
PMID:10786832
Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome.