Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs using Ensembl Compara
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
Gene Ontology annotation based on curation of immunofluorescence data
Gene Ontology annotation based on LIFEdb localization data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.
Towards a proteome-scale map of the human protein-protein interaction network.
UBE1DC1, an ubiquitin-activating enzyme, activates two different ubiquitin-like proteins.
Network organization of the human autophagy system.
A directed protein interaction network for investigating intracellular signal transduction.
Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Modification of ASC1 by UFM1 is crucial for ERĪ± transactivation and breast cancer development.
A proteome-scale map of the human interactome network.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
UBA5 mutations cause a new form of autosomal recessive cerebellar ataxia.
Structural and functional analysis of a novel interaction motif within UFM1-activating enzyme 5 (UBA5) required for binding to ubiquitin-like proteins and ufmylation.
Biallelic variants in UBA5 reveal that disruption of the UFM1 cascade can result in early-onset encephalopathy.
Trans-binding mechanism of ubiquitin-like protein activation revealed by a UBA5-UFM1 Complex.
Architecture of the human interactome defines protein communities and disease networks.
Trans-binding of UFM1 to UBA5 stimulates UBA5 homodimerization and ATP binding.
Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development.
An N-terminal extension to UBA5 adenylation domain boosts UFM1 activation: isoform-specific differences in ubiquitin-like protein activation.
Ribosomal protein RPL26 is the principal target of UFMylation.
An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5.
A genome-wide ER-phagy screen highlights key roles of mitochondrial metabolism and ER-Resident UFMylation.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
A concerted action of UBA5 C-terminal unstructured regions is important for transfer of activated UFM1 to UFC1.
Structural basis for UFM1 transfer from UBA5 to UFC1.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation.
Multimodal cell maps as a foundation for structural and functional genomics.