Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells.

Inactivating PAPSS2 mutations in a patient with premature pubarche.

Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.

Clinical and radiographic features of the autosomal recessive form of brachyolmia caused by PAPSS2 mutations.

A reference map of the human binary protein interactome.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS

PAPSS1,2 transfer SO4(2-) group to ATP to form APS

Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS

Defective PAPSS2 does not transfer SO4(2-) group to ATP to form APS