GO_REF:0000044

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

PMID:21219636

Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth.

ANKRD46 is a direct miR-21 target.

"Knockdown of miR-21 significantly increased the expression of ANKRD46 at both mRNA and protein levels."

PMID:25550434

Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells.

Anti-miR-21 induces ANKRD46.

"Uptake of anti-miR-21, but not a mismatch (MM) control, induces expression of known miR-21 targets (DDAH1, ANKRD46)"

PMID:35271311

OpenCell: Endogenous tagging for the cartography of human cellular organization.

PMID:25542822

MicroRNA-451 plays a role in murine embryo implantation through targeting Ankrd46, as implicated by a microarray-based analysis.

file:human/ANKRD46/ANKRD46-uniprot.txt

UniProt entry Q86W74 (ANR46_HUMAN)

file:interpro/panther/PTHR22677/PTHR22677-entries.csv

PTHR22677 family members

file:human/ANKRD46/ANKRD46-bioinformatics/RESULTS.md

ANKRD46 OpenCell localization

file:human/ANKRD46/ANKRD46-deep-research-affinage.md

Affinage mechanistic annotation for ANKRD46 (human)