Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Combined Automated Annotation using Multiple IEA Methods

Barttin increases surface expression and changes current properties of ClC-K channels.

Disease-causing dysfunctions of barttin in Bartter syndrome type IV.

A reference map of the human binary protein interactome.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region

UniProtKB Q8WZ55 human barttin record

Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.

Atypical Bartter syndrome with sensorineural deafness with G47R mutation of the beta-subunit for ClC-Ka and ClC-Kb chloride channels, barttin.

Barttin modulates trafficking and function of ClC-K channels.

Molecular basis of DFNB73: mutations of BSND can cause nonsyndromic deafness or Bartter syndrome.

Barttin activates ClC-K channel function by modulating gating.

Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.