GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:15759005
The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.
PMID:24739963
Juno is the egg Izumo receptor and is essential for mammalian fertilization.
PMID:27309808
Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.
PMID:39423812
A conserved fertilization complex bridges sperm and egg in vertebrates.
Reactome:R-HSA-1297275
CD9:Izumo Binding
PMID:36070373
MAIA, Fc receptor-like 3, supersedes JUNO as IZUMO1 receptor during human fertilization.
file:human/IZUMO1/IZUMO1-uniprot.txt
UniProt record Q8IYV9 (IZUMO1)