Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.
The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks.
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.
The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks.
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M.
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM.
A proteome-scale map of the human interactome network.
A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency.
A reference map of the human binary protein interactome.
DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
FANCM:FAAP24 and APITD1:STRA13 bind ICL-DNA
FA core complex assembles at DNA interstrand crosslinks (ICLs)
FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex
Monoubiquitination of FANCD2:FANCI
DNA nucleases bind monoubiquitinated ID2 complex
DNA nucleases unhook the interstrand crosslink (ICL)
Translesion synthesis across unhooked ICL by POLN
FANCD2 deubiquitination by USP1:WDR48
The complex of ATR and ATRIP is recruited to ICL-DNA
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA
FA core complex:HSP70s binds PKR
The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair.
The fission yeast FANCM ortholog directs non-crossover recombination during meiosis.
Regulation of mitotic recombination between DNA repeats in centromeres.
Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.
Biochemical Activities and Genetic Functions of the Drosophila melanogaster Fancm Helicase in DNA Repair.
Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.
The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription.
FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops.
Human Protein Atlas subcellular localization of FANCM (ENSG00000187790)
FANCM and FAAP24 maintain genome stability via cooperative as well as unique functions.