Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer's disease.
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ASAH2L is a partial paralog of ASAH2 with reduced expression in LOAD.
"We discovered this gene while studying the alkaline ceramidase gene (ASAH2); it is a partial paralog of ASAH2, and we call it ASAH2L."
ASAH2B coverage of the neutral ceramidase ASAH2
UniProt entry P0C7U1 (ASA2B_HUMAN)
Affinage mechanistic annotation for ASAH2B (human)