GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

InterPro supplied broad channel, membrane, and transmembrane-transport parent annotations.

GO_REF:0000120

Combined automated GO annotation using multiple IEA methods

Automated InterPro/PANTHER/UniRule mapping supplies the specific water channel and water transport annotations.

file:PSEPK/aqpZ/aqpZ-uniprot.txt

UniProtKB reviewed entry for aqpZ

UniProt identifies AqpZ as a homotetrameric inner-membrane aquaporin water channel.

file:PSEPK/aqpZ/aqpZ-goa.tsv

QuickGO GOA annotations for aqpZ

file:interpro/panther/PTHR19139/PTHR19139-metadata.yaml

PANTHER family metadata for aqpZ

file:PSEPK/aqpZ/aqpZ-deep-research-falcon.md

Falcon (Edison Scientific) deep research report on aqpZ (Q88F17, PP_4282) in Pseudomonas putida KT2440

Q88F17 is best annotated as a **water-selective aquaporin (AqpZ-like)** that increases membrane water permeability.
AqpZ (Q88F17) is likely an inner-membrane aquaporin that facilitates rapid, selective transmembrane water flux (osmotic water permeability).
functional data summarized in authoritative prokaryotic aquaporin reviews indicate that AqpZ behaves as an “exclusive water facilitator” (water transport detectable; glycerol/urea transport not detected in standard assays).
PP_4282 is expected to localize to the **cytoplasmic (inner) membrane** of this Gram-negative bacterium and form tetramers, with **one functional water pore per monomer**.
AqpZ in canonical bacterial contexts supports **rapid water influx/efflux during sudden osmotic shifts** (hypo-osmotic induction noted; role in osmoregulation and competitive viability).
no primary experimental study was found that directly characterizes PP_4282/Q88F17