Reviewed every one of the 10 original annotations and all core functions using the review and annotation-reviewer workflows. Machine payloads, row order, evidence codes, qualifiers, source identifiers and WITH/FROM values were preserved. No NEW rows were added.
Native car2 deletion strongly reduces arginine-carbon conversion into proline/glutamate-related amino acids (PMID:20460254); PMID:26075619 shows that deleting car2 does not remove the arginase-dependent heavy-nitrogen/urea route. Thus car2 deletion and car1/aru1 double deletion are not interchangeable mechanistically. Cytosolic localization is supported, but the old mitochondrial IBA REMOVE overreached: cytoplasmic/nuclear observations and an unverified impression of targeting sequence do not exclude dual localization. The mitochondrial row is now UNDECIDED with source-specific PTN metadata. The proline-producing role is retained non-core, with labeling conditions stated. The exact pro3/put1/put2 shuttle in pombe remains to be tested.
Normal publication caching passed. Genuine Falcon research with Perplexity-lite fallback was attempted for this gene; authentication/quota errors prevented a report. Manual source review is recorded here, with no fabricated provider-named research file. Abstract-only and bibliographic-only access are distinguished from full text; unknown target supplementary details are not treated as a contradiction. Logs are under .cache/module-audit-logs/arginase-SCHPO-car2-*.
The initial focused validation passed. Record sections are backfilled, and final schema/term/reference validation, rendering and helper-history checks are recorded in the same log directory. Actions: ACCEPT 6, KEEP_AS_NON_CORE 2, MODIFY 1, UNDECIDED 1.