Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Identification of a human heme exporter that is essential for erythropoiesis.
Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin.
Mutations of FLVCR1 in posterior column ataxia and retinitis pigmentosa result in the loss of heme export activity.
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation.
Quantitative fragmentomics allow affinity mapping of interactomes.
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals.
Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Molecular mechanism of choline and ethanolamine transport in humans.
Biallelic variation in the choline and ethanolamine transporter FLVCR1 underlies a severe developmental disorder spectrum.
Diversity of human choline transporters: substrate specificity, kinetic properties, and inhibitor sensitivity.
FLVCR1-1 transports heme from cytosol to extracellular region
Iron uptake and transport
FLVCR1-2 transports heme from mitochondrial matrix to cytosol
FLVCR1 source evidence, original annotation contexts and natural-product boundaries