GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000003
Gene Ontology annotation based on Enzyme Commission mapping
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000116
Automatic Gene Ontology annotation based on Rhea mapping
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:1739968
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.
PMID:2038314
Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae.
PMID:10504407
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase.
PMID:12176355
Activation of GCN2 in UV-irradiated cells inhibits translation.
PMID:16054071
The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores.
PMID:16121183
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2.
PMID:16601681
Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses.
PMID:17369398
A novel checkpoint mechanism regulating the G1/S transition.
PMID:19033384
The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint.
PMID:23447528
IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth.
PMID:24310610
Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation.
PMID:25329545
p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity.
PMID:26102367
Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress.
PMID:32610081
Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate.
PMID:39947182
The integrated stress response regulates 18S nonfunctional rRNA decay in mammals.
file:human/EIF2AK4/EIF2AK4-source-guide.md
EIF2AK4 source guide
file:human/EIF2AK4/EIF2AK4-uniprot.txt
UniProtKB Q9P2K8 (EIF2AK4) curated record