GO_REF:0000003
Gene Ontology annotation based on Enzyme Commission mapping
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000054
Gene Ontology annotation based on curation of intracellular localizations of expressed fusion proteins in living cells
GO_REF:0000104
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:25152161
Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis.
PMID:27499296
Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.
PMID:28927698
Biochemistry of Mitochondrial Coenzyme Q Biosynthesis.
PMID:30659264
Clinical phenotype, in silico and biomedical analyses, and intervention for an East Asian population-specific c.370G>A (p.G124S) COQ4 mutation in a Chinese family with CoQ10 deficiency-associated Leigh syndrome.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:38014483
Biallelic COQ4 Variants in Hereditary Spastic Paraplegia: Clinical and Molecular Characterization.
PMID:38295803
COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells.
PMID:38425362
In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis.
Reactome:R-HSA-2142789
Ubiquinol biosynthesis
Reactome:R-HSA-2162186
COQ3 methylates DeMQ10H2
Reactome:R-HSA-2162187
COQ6 hydroxylates DHB
Reactome:R-HSA-2162188
COQ5 methylates MDMQ10H2
Reactome:R-HSA-2162193
COQ3 methylates DHDB
Reactome:R-HSA-2162194
COQ7:COQ9 octamer hydroxylates DMQ10H2
Reactome:R-HSA-2162195
COQ4 decarboxylates MHDB