Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Combined Automated Annotation using Multiple IEA Methods
Deep research summary for PGRPS1 in Anopheles gambiae
-
PGRP-S1 lacks catalytic residues and is SA-like ortholog
"PGRP-S1 is best (though weakly) recognized as the putative ortholog of Drosophila PGRP-SA"
-
PGRP-S1 is a non-catalytic receptor, not an amidase
"PGRP-S1 [...] lacks conserved Zn/catalytic residues (predicted non-amidase)"
-
Short PGRPs S2/S3 retain amidase activity unlike S1
"among short PGRPs (S1, S2, S3), S2/S3 retain catalytic residues (predicted amidases), whereas S1 does not"