GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000114
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:10358019
EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins.
PMID:10821830
Self-assembly and supramolecular organization of EMILIN.
PMID:11278945
Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily.
PMID:16189514
Towards a proteome-scale map of the human protein-protein interaction network.
PMID:16893474
Elastic fibres in health and disease.
PMID:17988845
EMILINs interact with anthrax protective antigen and inhibit toxin action in vitro.
PMID:18463100
The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin.
PMID:19447967
Shifted Transversal Design smart-pooling for high coverage interactome mapping.
PMID:20551380
Proteomics characterization of extracellular space components in the human aorta.
PMID:21362503
Protein profile of exosomes from trabecular meshwork cells.
PMID:21516116
Next-generation sequencing to generate interactome datasets.
PMID:22566882
The EMILIN/Multimerin family.
PMID:23658023
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.
PMID:23979707
SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
PMID:25037231
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:26462740
Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease.
PMID:26627825
Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes.
PMID:27068509
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
PMID:28327460
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
PMID:28675934
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
PMID:29892012
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
Reactome:R-HSA-2161282
Elastic fibres bind associated proteins
PMID:12456677
beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain.
PMID:14701737
EMILIN-1 deficiency induces elastogenesis and vascular cell defects.
PMID:16530041
Emilin1 links TGF-beta maturation to blood pressure homeostasis.
PMID:18757743
Transcriptome-based systematic identification of extracellular matrix proteins.
PMID:21949412
EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation.
PMID:22814752
Vascular smooth muscle Emilin-1 is a regulator of arteriolar myogenic response and blood pressure.
PMID:25056700
TGF-β mediates early angiogenesis and latent fibrosis in an Emilin1-deficient mouse model of aortic valve disease.
PMID:28717224
Fibulin-4 deposition requires EMILIN-1 in the extracellular matrix of osteoblasts.
PMID:36351433
EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis.
file:human/EMILIN1/EMILIN1-source-guide.md
EMILIN1 source and assay guide
file:human/EMILIN1/EMILIN1-bioinformatics/RESULTS.md
EMILIN1 reproducible source-context analysis