Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

GO_REF:0000122

AtSubP analysis

PMID:10948255

AINTEGUMENTA promotes petal identity and acts as a negative regulator of AGAMOUS.

Characterizes the AP2 transcription factor AINTEGUMENTA; used as family-analogy (IC) support for nuclear localization of AP2 factors such as WRI1.

PMID:11118137

Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.

Genome-wide TF classification placing WRI1 among AP2/EREB DNA-binding transcription factors.

PMID:15500472

WRINKLED1 encodes an AP2/EREB domain protein involved in the control of storage compound biosynthesis in Arabidopsis.

Identifies WRI1 as an AP2/EREB transcription factor controlling seed storage compound (oil) biosynthesis.

PMID:15753106

ACTIVATOR of Spomin::LUC1/WRINKLED1 of Arabidopsis thaliana transactivates sugar-inducible promoters.

WRI1 transactivates sugar-inducible promoters, linking it to sugar signaling.

PMID:16553903

A spatiotemporal analysis of enzymatic activities associated with carbon metabolism in wild-type and mutant embryos of Arabidopsis using in situ histochemistry.

wri1 embryos show altered carbon-metabolism enzyme activities, consistent with WRI1 control of the glycolytic program feeding oil synthesis.

PMID:19719479

Role of WRINKLED1 in the transcriptional regulation of glycolytic and fatty acid biosynthetic genes in Arabidopsis.

WRI1 directly binds and activates promoters of glycolytic and fatty acid biosynthetic genes (AW-box), establishing direct DNA binding.

PMID:19755540

Analysis of metabolic flux phenotypes for two Arabidopsis mutants with severe impairment in seed storage lipid synthesis.

wri1 is among mutants with severe impairment in seed storage lipid synthesis.

PMID:23243127

WRINKLED transcription factors orchestrate tissue-specific regulation of fatty acid biosynthesis in Arabidopsis.

WRI clade members regulate fatty acid/cutin biosynthesis in a tissue-specific manner.

PMID:23922666

Wrinkled1, a ubiquitous regulator in oil accumulating tissues from Arabidopsis embryos to oil palm mesocarp.

WRI1 is a conserved, ubiquitous regulator of oil accumulation across tissues and species.

PMID:28314829

Phosphorylation of WRINKLED1 by KIN10 Results in Its Proteasomal Degradation, Providing a Link between Energy Homeostasis and Lipid Biosynthesis.

WRI1 physically interacts with the SnRK1/KIN10 kinase, which controls WRI1 protein stability in response to sugar status.

PMID:9733529

wrinkled1: A novel, low-seed-oil mutant of Arabidopsis with a deficiency in the seed-specific regulation of carbohydrate metabolism.

The wrinkled1 mutant is impaired in conversion of seed carbohydrate to oil, establishing WRI1's role in lipid biosynthesis and carbohydrate metabolism.

file:ARATH/WRI1/WRI1-deep-research-falcon.md

Falcon/Edison deep research report for WRI1/WRINKLED1, Arabidopsis thaliana

Synthesizes WRI1 as the nuclear AP2/EREB master regulator of seed oil biosynthesis that binds the AW-box and activates glycolytic and fatty acid synthesis genes; wri1 mutants have ~80% lower seed oil; regulated by SnRK1/KIN10, 14-3-3, and bZIP52 within the LEC1/LEC2/FUS3 network.