GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/gcvH1/gcvH1-uniprot.txt

UniProtKB entry for gcvH1 (Q88P64)

The reviewed HAMAP-backed record identifies a covalently lipoylated GcvH carrier that transfers the methylamine intermediate from P to T protein.

file:PSEPK/gcvH1/gcvH1-goa.tsv

QuickGO GOA annotations for gcvH1

file:interpro/panther/PTHR11715/PTHR11715-metadata.yaml

PANTHER glycine cleavage H-protein family metadata

PMID:27303730

GcsR, a TyrR-Like Enhancer-Binding Protein, Regulates Expression of the Glycine Cleavage System in Pseudomonas aeruginosa PAO1.

P. aeruginosa has two GCS gene sets and coordinately regulates its gcs2 operon in response to glycine.

"these five genes are transcribed together as a single operon"

file:projects/P_PUTIDA/deep-research/PSEPK__glycine_cleavage_system__ppu00260-deep-research-openscientist.md

OpenScientist PSEPK glycine cleavage system synthesis

PMID:20508247

Lipoic acid metabolism in microbial pathogens.

In E. coli, LipB transfers octanoate from octanoyl-ACP directly to apo-lipoyl domains and LipA then inserts the sulfur atoms; no H-protein relay is needed.

"LipB transfers an octanoyl group from octanoyl acyl carrier protein (octanoyl-ACP) to the apoprotein."

file:modules/glycine_cleavage_system.yaml

Glycine cleavage system module