ASNSD1 notes

• Dark protein. The only phenotype is PMID:32638637. No muscle process is annotated, because it is necessity evidence with no mechanism.
• The affinage narrative is mostly about ASDURF, the uORF microprotein (PAQosome subunit; PMID:31738558, PMID:38176414). It is a different gene product, and its PAQosome/chaperone grounding is not applied to Q9NWL6.
• 24 PDZ-screen protein-binding rows (PMID:36115835, PMID:30126976) are changed (MODIFY) to GO:0030165 PDZ domain binding, as for NRXN3 from the same screen. All 22 unique partners are PDZ proteins, and the ASNSD1 C-terminus ends ...IEKETKL, a class I PBM. The one BioPlex AP-MS row (PDZK1) is removed. Q86UT5 is listed under its current HGNC symbol NHERF4 (formerly PDZD3).
• The MF ND row is removed (superseded by PDZ domain binding); the CC and BP ND rows are accepted. The core function is the PBM/PDZ binding, with the catalytic question kept in a WHOLLY_DARK gap.
• The liver-fibrosis NS3TP1 studies (PMID:37274069, PMID:36983568) are not cached and not used.
• ASDURF has its own review at genes/human/ASDURF/.