MPG1 (P52751) notes — Magnaporthe oryzae class I hydrophobin

Sources

• UniProt P52751; Falcon deep research (MPG1-deep-research-falcon.md); cached PMIDs 8312740, 12239409, 8755621, 12481998, 15773983 (abstract only) and 27142249 (full text).

Key facts

• Secreted class I hydrophobin: PMID:12239409
• Builds the conidial rodlet layer: PMID:12239409; PMID:27142249
• Interface-driven amyloid assembly: PMID:27142249
• Disulphides needed for secretion not assembly: PMID:15773983
• Mutant phenotype (necessity evidence): PMID:8312740; easily wettable.
• Surface recognition: PMID:8755621 Defect rescued in trans by WT cells and (per deep research) by cAMP.
• Regulation: PMK1, NPR1, NUT1 required for starvation expression; CPKA represses PMID:12481998.
• Cut2 retention by MPG1 coatings in vitro only PMID:27142249.

Curation decisions

• All 5 GOA rows (structural constituent of cell wall IEA; extracellular region EXP x2 + IEA; fungal-type cell wall IEA) ACCEPTED.
• NEW: spore wall (GO:0031160) and asexual spore wall assembly (GO:0042243). Comparator check via QuickGO: A. fumigatus RodA P41746 has GO:0031160 EXP; A. nidulans RodA P28346 has GO:0031160 IDA/EXP and GO:0042243 IMP. MPG1 is the self-assembling subunit, so passes participation.
• Deliberately NOT proposed: appressorium formation, conidium formation, pathogenesis / host-interaction terms — supported only by mutant (necessity) phenotypes; mechanism (sensor vs adhesion) unresolved. No GOA row uses host-interaction terms.