Annotation inferences using phylogenetic trees
Combined Automated Annotation using Multiple IEA Methods
The AauR-AauS two-component system regulates uptake and metabolism of acidic amino acids in Pseudomonas putida.
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The paper studies the AauR-AauS two-component system controlling acidic amino acid uptake and metabolism in P. putida KT2440; it does not concern DadA or PA5084.
"Here, we show that the two-component system encoded by PP1067-PP1066 ( aauS-aauR ) is required for efficient growth of P. putida KT2440 on acidic amino acids (Glu and Asp) and their amides (Gln and Asn)."
Regulation and characterization of the dadRAX locus for D-amino acid catabolism in Pseudomonas aeruginosa PAO1.
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Purified DadA1 (PA5304) is a broad-specificity D-amino acid dehydrogenase and is the enzyme solely responsible for the D-amino acid dehydrogenase activity in PAO1.
"the results from this study clearly demonstrate DadA to be the enzyme solely responsible for the proposed D-amino acid dehydrogenase activity of broad substrate specificity"
UniProt entry Q9HU99 (DADA2_PSEAE)