-u P50514.Reviewed all 10 existing rows and the core functions with the review and annotation-reviewer workflows. Preserved every machine-sourced term, evidence code, qualifier, source identifier, WITH/FROM entry and row order. No new annotations were added in this audit.
PMID:32896087 supports arginine auxotrophy after arg41 deletion under the tested conditions, not quantitative dominance in every condition. The catalytic assignment also rests on conserved lyase architecture and phylogenetic inference; knockout alone is not a direct enzyme assay. Suggested experiments now ask for paralog-specific activity/flux rather than treating phenotype as an assay substitute.
Live GO:0000050 describes ornithine-to-arginine synthesis followed by arginine cleavage to urea and regenerated ornithine; it does not require ureotelic nitrogen excretion. PMID:20435771 directly measures S. pombe Car1/Car3 arginase-dependent urea production, and PMID:18849471 explicitly places OTC in the urea-cycle segment. Existing OTC/ASS/ASL rows are retained as non-core participation in this reaction topology, without asserting net full-cycle flux or universal simultaneous operation. The upstream acetylornithine-producing Arg1 is treated separately.
Normal publication caching completed. Normal Falcon research with Perplexity-lite fallback was attempted for this gene; authentication/quota failures prevented a generated report. Manual review used the actual cached primary sources and curated UniProt, and no provider-named research file was fabricated. Per-gene attempts and validation logs are in .cache/module-audit-logs/arginine-SCHPO-arg41-*. Abstract-only or bibliographic-only sources are distinguished from full text in reference reviews; unavailable source details are not treated as experimental refutations.
Actions: ACCEPT 7, KEEP_AS_NON_CORE 2, MODIFY 1. Record sections were backfilled; focused schema/reference validation passed on the initial complete panel. Final targeted checks and HTML rendering are recorded in the audit logs.