FUL (FRUITFULL, AGL8, At5g60910; UniProt Q38876) curation notes

2026-10-05 — initial review (floral_meristem_identity module)

• Identity: UniProt primary gene name is AGL8 (synonym FUL); fetched by accession
  (just fetch-gene ARATH Q38876 --alias FUL) and gene_symbol set to the standard TAIR symbol FUL.
• Falcon deep research attempted; the provider failed (exit code 1). Notes are from cached publications.

Floral transition and meristem identity

• AGL8 is expressed in the inflorescence meristem, stem and cauline leaves, excluded from floral primordia, partly by AP1
  PMID:8535133
• Rapid induction at the apex during photoinduction PMID:9367440
• ap1 cal ful non-flowering phenotype; LFY not up-regulated, TFL1 ectopic PMID:10648231.
• FT-dependent accumulation PMID:16155177
• SPLs (age pathway) directly activate flower-promoting MADS-box genes PMID:19703399.
• FUL redundantly with SOC1 promotes flowering; heterodimer model
  PMID:24465009.
• soc1 ful double mutants: perennial-like phenotypes, meristem determinacy PMID:18997783

Fruit and other roles

• Fruit: PMID:9502732
• Stem/branch growth via SAUR10 PMID:28586421.
• End of flowering (global proliferative arrest) via direct AP2 repression PMID:29422669.

Decisions

• Core MF GO:0000981; core BPs GO:0010228 (vegetative to reproductive phase transition of meristem; supported by Balanza 2014 and Hempel 1997, not in GOA), GO:0009911 (existing), GO:0010154 fruit development (existing IMP).
• All protein binding IPI rows (SEP3, SOC1, AGL24 partners) -> MODIFY to GO:0046982.
• GO:0010077 IGI with BOP1/2 (abstract-only paper) -> KEEP_AS_NON_CORE, deferring to the curator; same decision used for the SOC1 row from the same paper.
• GO:0060560 (SAUR10 / branch growth) and the Y1H nitrogen network row -> KEEP_AS_NON_CORE.