Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
Combined Automated Annotation using Multiple IEA Methods
Tau promoter confers neuronal specificity and binds Sp1 and AP-2.
A family of AP-2 proteins down-regulate manganese superoxide dismutase expression.
Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis.
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.
Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.
Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation.
Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter.
The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation.
BCOR regulates mesenchymal stem cell function by epigenetic mechanisms.
Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins.
AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes.
AP2 transcription factor induces apoptosis in retinoblastoma cells.
Expression of human frataxin is regulated by transcription factors SRF and TFAP2.
Dual association by TFAP2A during activation of the p21cip/CDKN1A promoter.
Genotype-phenotype analysis of the branchio-oculo-facial syndrome.
Sumoylation pathway is required to maintain the basal breast cancer subtype.
A proteome-scale map of the human interactome network.
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Architecture of the human interactome defines protein communities and disease networks.
Androgen upregulates NR4A1 via the TFAP2A and ETS signaling networks.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
KCTD1 mutants in scalp‑ear‑nipple syndrome and AP‑2α P59A in Char syndrome reciprocally abrogate their interactions, but can regulate Wnt/β‑catenin signaling.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Cloning and characterization of a second AP-2 transcription factor: AP-2 beta.
Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression.
An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2.
Derepression of the C/EBPalpha gene during adipogenesis: identification of AP-2alpha as a repressor.
AP-2 (TFAP2) transcription factors form homo- and heterodimers
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
KCTD1 binds TFAP2 homo- and heterodimers
TFAP2A,TFAP2C homodimers bind ESR1 promoter
TFAP2A,TFAP2C homodimers bind the CGA gene
TFAP2A,TFAP2C homodimers bind the CGB gene promoter
TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers bind the ERBB2 gene promoter and recruit YY1
TFAP2A,(TFAP2B) homodimers bind the KIT gene promoter
TFAP2A,TFAP2C homodimers:CITED2 binds PITX2 gene promoter
TFAP2A homodimer binds the VEGFA gene promoter
TFAP2A homodimer binds the TGFA gene promoter
TFAP2A homodimer binds CDKN1A (p21) gene
TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter
TFPA2A homodimer and NPM1 bind the NOP2 gene promoter
TFPA2A homodimer and NPM1 bind the MYBL2 gene promoter
NPM1 binds TFAP2A homodimer
TFAP2A in complex with DEK binds the APOE gene promoter
DEK binds TFAP2A homodimers
RB1 and TFAP2A bind CDH1 gene promoter
MITF-M dimer and TFAP2A bind intronic elements in the IRF4 gene
Amphioxus and lamprey AP-2 genes: implications for neural crest evolution and migration patterns.
Induction of neural crest in Xenopus by transcription factor AP2alpha.
Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory network.
Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification.
lockjaw encodes a zebrafish tfap2a required for early neural crest development.
Neural crest survival and differentiation in zebrafish depends on mont blanc/tfap2a gene function.
Redundant activities of Tfap2a and Tfap2c are required for neural crest induction and development of other non-neural ectoderm derivatives in zebrafish embryos.
Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects.
Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population.
Inhibition of neural crest formation by Kctd15 involves regulation of transcription factor AP-2.
Tfap2 transcription factors in zebrafish neural crest development and ectodermal evolution.
TFAP2A mutations result in branchio-oculo-facial syndrome.
Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2.
Transcription factor AP-2 essential for cranial closure and craniofacial development.
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis.
Deep research report on TFAP2A (Falcon)
UniProt entry P05549 (TFAP2A_HUMAN)