GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000113
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10207087
Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.
PMID:10867017
The hematopoietic transcription factor PU.1 represses gelatinase A transcription in glomerular mesangial cells.
PMID:12833137
CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells.
PMID:15304486
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.
PMID:18250304
Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia.
PMID:18692240
Physical and functional interactions between hematopoietic cell-specific ETS transcription factors and homeodomain proteins.
PMID:20139074
Metallothionein-1 isoforms and vimentin are direct PU.1 downstream target genes in leukemia cells.
PMID:20159610
PML/RARalpha targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemia.
PMID:20972335
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis.
PMID:21575865
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.
PMID:2180582
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene.
PMID:24429361
Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis.
PMID:24504023
Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes.
PMID:26019275
A Novel In-Frame Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency.
PMID:27506447
Transcriptional regulation of the proto-oncogene Zfp521 by SPI1 (PU.1) and HOXC13.
PMID:28111278
Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages.
PMID:28362429
PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression.
PMID:28481873
Restoring PU.1 induces apoptosis and modulates viral transactivation via interferon-stimulated genes in primary effusion lymphoma.
PMID:29290617
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification.
PMID:30429596
In vitro conversion of adult murine endothelial cells to hematopoietic stem cells.
PMID:30718772
A transcription factor PU.1 is critical for Ccl22 gene expression in dendritic cells and macrophages.
PMID:31018969
A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.
PMID:31146003
Androgen upregulates NR4A1 via the TFAP2A and ETS signaling networks.
PMID:31314592
PU.1 plays a pivotal role in dendritic cell migration from the periphery to secondary lymphoid organs via regulating CCR7 expression.
PMID:33951726
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.
Reactome:R-HSA-9617064
SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
Reactome:R-HSA-9617207
SPI1 (PU.1), CEBPA and DEK bind the promoter of the CSF3R (G-CSFR) gene
PMID:23658224
Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1.