Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Electronic Gene Ontology annotations created by ARBA machine learning models

The Drosophila caspase DRONC is regulated by DIAP1.

Caspases function in autophagic programmed cell death in Drosophila.

Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.

Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development.

Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery.

The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process.

DRONC coordinates cell death and compensatory proliferation.

The Drosophila caspases Strica and Dronc function redundantly in programmed cell death during oogenesis.

DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells.

Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals.

Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc.

Differential localization and processing of apoptotic proteins in Malpighian tubules of Drosophila during metamorphosis.

Drosophila caspases involved in developmentally regulated programmed cell death of peptidergic neurons during early metamorphosis.

Caspase-dependent regulation of the ubiquitin-proteasome system through direct substrate targeting.

Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression.

Drice restrains Diap2-mediated inflammatory signalling and intestinal inflammation.

Apoptotic caspase inhibits innate immune signaling by cleaving NF-κBs in both Mammals and Flies.

Identification of a Drosophila melanogaster ICE/CED-3-related protease, drICE.