Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Biogenesis and proteolytic processing of lysosomal DNase II.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Architecture of the human interactome defines protein communities and disease networks.
Type I interferon-mediated autoinflammation due to DNase II deficiency.
Janus kinase inhibition for autoinflammation in patients with DNASE2 deficiency.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation.
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver.
Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Molecular cloning of the cDNA encoding human deoxyribonuclease II.
The cloning and expression of human deoxyribonuclease II. A possible role in apoptosis.
DNase II is a member of the phospholipase D superfamily.
Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy.
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
DNase II-dependent DNA digestion is required for DNA sensing by TLR9.
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
DNase II Can Efficiently Digest RNA and Needs to Be Redefined as a Nuclease.
The phylogeny and evolution of deoxyribonuclease II: an enzyme essential for lysosomal DNA degradation.
NUC-1, a caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis.
Proteolytic processing of porcine deoxyribonuclease II occurs in lysosomes but is not required for enzyme activation.
UniProt entry O00115 (DNASE2_HUMAN)