GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:10103013
Expression of receptors for human angiogenin in vascular smooth muscle cells.
PMID:10413501
Superadditive and subadditive effects of "hot spot" mutations within the interfaces of placental ribonuclease inhibitor with angiogenin and ribonuclease A.
PMID:10649442
Human angiogenin is rapidly translocated to the nucleus of human umbilical vein endothelial cells and binds to DNA.
PMID:10999833
Evidence for the presence of angiogenin in human follicular fluid and the up-regulation of its production by human chorionic gonadotropin and hypoxia.
PMID:11438326
Concentrations of angiogenic factors in follicular fluid and oocyte-cumulus complex culture medium from women undergoing in vitro fertilization: association with oocyte maturity and fertilization.
PMID:11782452
Antiplasmin activity of a peptide that binds to the receptor-binding site of angiogenin.
PMID:11919285
Diversifying selection of the tumor-growth promoter angiogenin in primate evolution.
PMID:11984825
Expression and localization of angiogenin in placenta: enhanced levels at term over first trimester villi.
PMID:12770725
Production of vascular endothelial growth factor and angiogenic factor in human follicular fluid.
PMID:15166501
Angiogenin distribution in human term placenta, and expression by cultured trophoblastic cells.
PMID:15735021
Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation.
PMID:15737636
Alpha-actinin-2, a cytoskeletal protein, binds to angiogenin.
PMID:15776477
Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival.
PMID:15979542
Hypoxia up-regulated angiogenin and down-regulated vascular cell adhesion molecule-1 expression and secretion in human placental trophoblasts.
PMID:16461950
Assessment of some tools for the characterization of the human osteoarthritic cartilage proteome.
PMID:16490744
Hypoxic conditions stimulate the production of angiogenin and vascular endothelial growth factor by human renal proximal tubular epithelial cells in culture.
PMID:16567967
Influence of angiogenin on the growth of A375 human melanoma cells and the expression of basic fibroblast growth factor.
PMID:17125737
Angiogenin-induced protein kinase B/Akt activation is necessary for angiogenesis but is independent of nuclear translocation of angiogenin in HUVE cells.
PMID:17991437
Identification and characterization of follistatin as a novel angiogenin-binding protein.
PMID:19332886
Angiogenin cleaves tRNA and promotes stress-induced translational repression.
PMID:20129916
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly.
PMID:21855800
Angiogenin-induced tRNA fragments inhibit translation initiation.
PMID:23047679
Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons.
PMID:23843625
Ribonuclease/angiogenin inhibitor 1 regulates stress-induced subcellular localization of angiogenin to control growth and survival.
PMID:2424496
Characteristic ribonucleolytic activity of human angiogenin.
PMID:24457100
Angiogenin interacts with the plasminogen activation system at the cell surface of breast cancer cells to regulate plasmin formation and cell migration.
PMID:2457905
Angiogenin activates endothelial cell phospholipase C.
PMID:2459697
Mutagenesis of aspartic acid-116 enhances the ribonucleolytic activity and angiogenic potency of angiogenin.
PMID:2479414
Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. Alanine derivatives inhibit angiogenin-induced angiogenesis.
PMID:25372031
Computational and functional characterization of Angiogenin mutations, and correlation with amyotrophic lateral sclerosis.
PMID:2646638
Angiogenin stimulates endothelial cell prostacyclin secretion by activation of phospholipase A2.
PMID:2730651
Characterization of ribonucleolytic activity of angiogenin towards tRNA.
PMID:2742853
Binding of placental ribonuclease inhibitor to the active site of angiogenin.
PMID:27518564
Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:28777577
Proteomic Analysis of Human Angiogenin Interactions Reveals Cytoplasmic PCNA as a Putative Binding Partner.
PMID:29100074
Plexin-B2 Mediates Physiologic and Pathologic Functions of Angiogenin.
PMID:29748193
Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor.
PMID:3122207
Ribonucleolytic activity of angiogenin: essential histidine, lysine, and arginine residues.
PMID:31582561
Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3-mediated gene silencing.
PMID:32510170
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
PMID:3289612
Base cleavage specificity of angiogenin with Saccharomyces cerevisiae and Escherichia coli 5S RNAs.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:3470787
Human placental ribonuclease inhibitor abolishes both angiogenic and ribonucleolytic activities of angiogenin.
PMID:3663649
Isolation of angiogenin from normal human plasma.
PMID:38718836
Structural mechanism of angiogenin activation by the ribosome.
PMID:4074709
Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells.
PMID:7679494
Actin is a binding protein for angiogenin.
PMID:8159680
Role of glutamine-117 in the ribonucleolytic activity of human angiogenin.
PMID:8448182
Characterization and sequencing of rabbit, pig and mouse angiogenins: discernment of functionally important residues and regions.
PMID:8570639
A combined kinetic and modeling study of the catalytic center subsites of human angiogenin.
PMID:8622921
The C-terminal region of human angiogenin has a dual role in enzymatic activity.
PMID:9122172
A putative angiogenin receptor in angiogenin-responsive human endothelial cells.
PMID:9245697
Interaction of human angiogenin with copper modulates angiogenin binding to endothelial cells.
PMID:9707554
Neomycin inhibits angiogenin-induced angiogenesis.
Reactome:R-HSA-5692437
ANG binds F-actin
Reactome:R-HSA-9708296
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis
Reactome:R-HSA-9708327
ANG cleaves tRNA to yield tRNA halves
file:human/ANG/ANG-deep-research-falcon.md
Falcon deep research report for human ANG