GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000043
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:15184064
Vitamin K-dependent Gas6 activates ERK kinase and stimulates growth of cardiac fibroblasts.
PMID:16359517
The role of gamma-carboxylation in the anti-apoptotic function of gas6.
PMID:16723520
Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis.
PMID:18395422
Endogenous Gas6 and Ca2+ -channel activation modulate phagocytosis by retinal pigment epithelium.
PMID:18680538
GAS6-induced signaling in human endothelial cells is mediated by FOXO1a.
PMID:18760998
Gas6-mediated signaling is dependent on the engagement of its gamma-carboxyglutamic acid domain with phosphatidylserine.
PMID:18840707
The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.
PMID:19657094
Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.
PMID:19922767
GAS6/Mer axis regulates the homing and survival of the E2A/PBX1-positive B-cell precursor acute lymphoblastic leukemia in the bone marrow niche.
PMID:20048160
Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testosterone on vascular calcification.
PMID:20088931
Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood.
PMID:20103767
TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages.
PMID:21501828
The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:7634325
Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3.
PMID:7854420
Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6.
PMID:8336730
The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.
Reactome:R-HSA-163809
Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus
Reactome:R-HSA-163843
Furin cleaves pro-GAS6 to GAS6
Reactome:R-HSA-202710
MERTK receptor binds ligands (Gas6 or Protein S)
Reactome:R-HSA-481007
Exocytosis of platelet alpha granule contents
Reactome:R-HSA-8952289
FAM20C phosphorylates FAM20C substrates
file:human/GAS6/GAS6-deep-research-falcon.md
Falcon deep research synthesis for GAS6