gcs-1 (Q20117) review notes

• Deep research failed (falcon timeout; perplexity unavailable). Review based on cached publications and UniProt.
• Catalytic subunit of glutamate-cysteine ligase (EC 6.3.2.2) PMID:16333752; mutants arsenic-sensitive, rescued by GSH PMID:16333752.
• SKN-1 target PMID:16166371.
• RNAi: needed for arsenite but hardly for juglone tolerance PMID:23593298 -- so the IMP "response to ROS" row is a broad reading; kept non-core.
• The interactome IPI partner Q966L2 (E01A2.1) is UniProt "Glutamate--cysteine ligase modifier subunit" (gclm-1), supporting the GCL complex IBA. Protein binding row removed as uninformative.
• Expression-response IEP rows (ROS, superoxide, heat) kept non-core; abstracts are cache-only so deferred to curators.