abaA (Aspergillus nidulans) — curation notes

UniProt: P20945 (ABAA_EMENI). TEA/ATTS-domain transcription factor; middle
regulator of the brlA -> abaA -> wetA conidiation cascade. Member of the
conidiation_regulatory_cascade module.

Core biology (with provenance)

• ATTS/TEA-domain sequence-specific DNA-binding transcriptional activator.
  AbaA binds 5'-CATTCY-3' (Y = pyrimidine) via major- and minor-groove contacts.
  PMID:8139553.
• Regulates the developmental gene network, including target structural genes
  and the regulators brlA, wetA and abaA itself.
  PMID:8139553.
• Controls phialide differentiation. abaA-null strains form aberrant
  conidiophores that make supernumerary metula-like cells instead of phialides
  and fail to produce conidia.
  PMID:2152124;
  PMID:2152124.
• Middle tier of the dependent pathway, activated by BrlA and activating WetA.
  PMID:2655931; cross-species: PMID:20966095.

Annotation-review summary

All 21 GOA annotations ACCEPTED — abaA is a cleanly characterized TF. Core MF
GO:0003700 (IDA, PMID:8139553); core BP phialide/conidiophore development and
positive regulation of conidium formation. No over-annotations identified.