Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network.
Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.
RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily.
ZNRF3 autoubiquitinates to promote its internalization
UniProt record O75473 (LGR5)