GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
PMID:38820162
Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy.
PMID:31769566
Recurrent arginine substitutions in the ACTG2 gene are the primary driver of disease burden and severity in visceral myopathy.
PMID:26647307
ACTG2 variants impair actin polymerization in sporadic Megacystis Microcolon Intestinal Hypoperistalsis Syndrome.
PMID:24337657
De novo ACTG2 mutations cause congenital distended bladder, microcolon, and intestinal hypoperistalsis.
PMID:36264152
Heterozygous Actg2(R257C) mice mimic the phenotype of megacystis microcolon intestinal hypoperistalsis syndrome.
PMID:40617346
Actg2(D245G) Mutation Causes Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome by Impairing Smooth Muscle Contractility.
PMID:30626964
SETD3 is an actin histidine methyltransferase that prevents primary dystocia.
PMID:10633868
Antisense oligodeoxynucleotide complementary to smooth muscle alpha-actin inhibits endothelial-mesenchymal transformation during chick cardiogenesis.
PMID:8006065
Actin isoform compartments in chicken gizzard smooth muscle cells.
PMID:21294755
Leptin and acetaldehyde synergistically promotes αSMA expression in hepatic stellate cells by an interleukin 6-dependent mechanism.
PMID:28320086
Antifibrotic effect of diethylcarbamazine combined with hesperidin against ethanol induced liver fibrosis in rats.
PMID:30476341
All-trans Retinoic Acid Disrupts Development in Ex Vivo Cultured Fetal Rat Testes. II: Modulation of Mono-(2-ethylhexyl) Phthalate Toxicity.
PMID:24743229
Structural differences explain diverse functions of Plasmodium actins.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:22516433
Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
PMID:23580065
Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.
Reactome:R-HSA-445699
ATP Hydrolysis By Myosin
Reactome:R-HSA-445700
Myosin Binds ATP
Reactome:R-HSA-445704
Calcium Binds Caldesmon
Reactome:R-HSA-445705
Release Of ADP From Myosin
Reactome:R-HSA-9914537
DGC complex binds AGRN and HSPG2
Reactome:R-HSA-9934294
CDH1-associated CTNNA1 binds VCL
Reactome:R-HSA-9934410
CDH1 forms homotypic trans-dimers
Reactome:R-HSA-9934486
CDH1-associated CTNNA1 binds F-actin
file:human/ACTG2/ACTG2-uniprot.txt
UniProtKB entry P63267 (ACTH_HUMAN), Actin, gamma-enteric smooth muscle
file:human/ACTG2/ACTG2-bioinformatics/RESULTS.md
ACTG2: a conventional actin with an entirely inferred GO record