Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells.

gammadelta T cells lyse autologous and allogenic oesophageal tumours: involvement of heat-shock proteins in the tumour cell lysis.

Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein.

The importance of a mobile loop in regulating chaperonin/ co-chaperonin interaction: humans versus Escherichia coli.

Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells.

Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring.

Lipopolysaccharide-free heat shock protein 60 activates T cells.

Detection of HSP60 on the membrane surface of stressed human endothelial cells by atomic force and confocal microscopy.

Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein.

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway.

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide.

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3.

Hsp60 regulation of tumor cell apoptosis.

Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors.

Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12.

Large-scale proteomics and phosphoproteomics of urinary exosomes.

Knockdown of human COX17 affects assembly and supramolecular organization of cytochrome c oxidase.

Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function.

Defining the membrane proteome of NK cells.

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

LAP, an alcohol acetaldehyde dehydrogenase enzyme in Listeria, promotes bacterial adhesion to enterocyte-like Caco-2 cells only in pathogenic species.

Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface.

Human 2'-phosphodiesterase localizes to the mitochondrial matrix with a putative function in mitochondrial RNA turnover.

Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.

Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer.

Next-generation sequencing to generate interactome datasets.

Parkin interacts with Ambra1 to induce mitophagy.

Toward an understanding of the protein interaction network of the human liver.

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A.

A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.

Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake.

GTP binding controls complex formation by the human ROCO protein MASL1.

Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression.

A proteome-scale map of the human interactome network.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

Widespread macromolecular interaction perturbations in human genetic disorders.

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Architecture of the human interactome defines protein communities and disease networks.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.

A Proteomic Variant Approach (ProVarA) for Personalized Medicine of Inherited and Somatic Disease.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

A reference map of the human binary protein interactome.

Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar Axoneme and Mitochondrial Sheath Defects and Asthenoteratozoospermia in Humans and Mice.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.

Differential CFTR-Interactome Proximity Labeling Procedures Identify Enrichment in Multiple SLC Transporters.

Multimodal cell maps as a foundation for structural and functional genomics.

PBP74, a new member of the mammalian 70-kDa heat shock protein family, is a mitochondrial protein.

Cell surface localization of the 60 kDa heat shock chaperonin protein (hsp60) in mammalian cells.

HSPD1 gene expression is repressed by the complex of NPM1 and TFAP2A homodimer

CLPXP binds mitochondrial matrix proteins

LONP1 degrades mitochondrial matrix proteins

LONP1 binds mitochondrial matrix proteins

CLPXP degrades mitochondrial matrix proteins

ATF5 and HSF1 trimer activate expression of HSPD1

UniProtKB P10809: human HSPD1 type I chaperonin sequence and mechanism

Crystal structure of the human mitochondrial chaperonin symmetrical football complex.

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space.

Fusion proteins containing the cytochrome b2 presequence are sorted to the mitochondrial intermembrane space independently of hsp60.

In organello formaldehyde crosslinking of proteins to mtDNA: identification of bifunctional proteins.

The role of heat shock proteins in inflammatory injury induced by cold stress in chicken hearts.