eca39 (SPBC428.02c, UniProt O14370) notes

• Single S. pombe branched-chain aminotransferase (BCAT, EC 2.6.1.42); homolog of S. cerevisiae BAT1/BAT2 and mammalian ECA39/BCAT.
• PMID:9483807; PMID:9483807 (abstract only).
• Pathway role: PMID:35325114; PMID:35325114; reversible PMID:35325114.
• Localisation: transit peptide 1-47 [UniProt:O14370]; PMID:35325114; UniProt Nucleus/Cytoplasm from ORFeome YFP. UniProt flags an erroneous earlier gene model (AAC39352.1) and a gene-model revision (PMID:21511999); whether the ORFeome clone was full-length is unknown.
• UniProt FUNCTION text emphasises catabolism ("first reaction in the catabolism"), but S. pombe evidence is biosynthetic (complements bat1 bat2 auxotrophy). Catabolic IBAs kept non-core.
• GO-CAM: two eca39 activities: GO:0052656 (Ile, matrix, part_of GO:1901705) and GO:0052654 (Leu, cytosol IC, part_of GO:0009098); no valine activity.
• Differs from S. cerevisiae: one BCAT doing both BAT1 (mitochondrial, biosynthetic) and BAT2 (cytosolic, catabolic) jobs. Core MF uses parent GO:0004084, as in BAT1 review; core location mitochondrion, with cytosol kept as non-core (IC).