GluA1 couples glutamate recognition to membrane conductance within AMPA receptors; interacting scaffolds organize receptor pools. [UniProtKB:P42261, CC:FUNCTION/SUBUNIT]
The review preserves 198 incoming records in the evidence sidecar and represents 192 schema contexts. One ECO-distinct pair and five date-only pairs share schema projections; the brain-extended pair remains separate. These projections do not assert identical evidence. Original ECO-specific reasons remain visible, and the current combined review is linked by pointer.
All ten manual slices were independently reviewed. Eighteen whole-gene specificity comparisons are recorded separately. Annotation qualifiers, product identifiers, partner groups and nine extension atoms are preserved. No NEW annotations are proposed.
The source guide distinguishes inspected originals, abstracts, curated transfers and unresolved assay details. Normal-cache availability is separate from access to private original evidence. Genuine no-force helpers produced the preserved 191-row PENDING seed and 198 downloaded GOA records, matching the private official inputs. The released 192-context projection restores all nine extension atoms. Ninety-four pre-existing normal sources and the additional GO-CAM source remain byte-identical; nineteen missing normal paths were acquired. Actual fetched titles and normal-cache availability are reconciled separately from original-reading limits. Validation, computed status, genuine CREATE history and rendering are recorded in the execution receipts.
Human HBGR1 supports agonist-responsive channels in Xenopus oocytes. PMID:1311100
Rat neuronal GluA1 colocalizes with auxiliary proteins in spines. PMID:21172611
GluA1 terminal peptides bind SAP97 PDZ2 under reducing conditions; oxidizing disulfide capture does not establish the physiological linkage. PMID:16634638
The original reports "dendritic spines, where CNIH-2 co-localized with both TARPs and GluA1". PMID:21172611
The original eighteen specificity comparisons remain historical provenance. This follow-up retains supported broad physiological compartments, distinguishes receptor readouts from demonstrated responses, and preserves the narrower unresolved source conjunction. All raw contexts, extension atoms, original ECO records and six alternative-product declarations remain unchanged. The functional-product model, source access, exact quote placements and independent phylogeny artifact are audited separately. Native acquisition and affected checks remain pending.
Native completion: the genuine helper fetched PMID22720072, all 113 prior source caches remained exact, and affected validation, strict GOA matching, computed status, EDIT history and rendering passed. The review remains DRAFT with one justified context-sensitive advisory. Final publication is pending its separate peer.
The existing context exception is now recorded in the schema-supported field, with its prior explanation relocated intact. One additional cached anchor is used once. All annotation actions, incoming contexts, products, source caches and previous evidence records remain unchanged. Affected native checks are pending.
Native completion: affected gene and reference validation, strict GOA matching, computed status and genuine EDIT-history checks passed. Annotation decisions and cached sources remain unchanged; actual rendering and final conservation checks are recorded separately.