Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization.
BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1.
Defining the human deubiquitinating enzyme interaction landscape.
The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.
BAP1 is phosphorylated at serine 592 in S-phase following DNA damage.
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.
The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex.
BRCA1-associated protein 1 (BAP1) deubiquitinase antagonizes the ubiquitin-mediated activation of FoxK2 target genes.
A High-Density Map for Navigating the Human Polycomb Complexome.
BAP1 regulates IP3R3-mediated Ca(2+) flux to mitochondria suppressing cell transformation.
A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.
BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Rare germline heterozygous missense variants in BRCA1-associated protein 1, BAP1, cause a syndromic neurodevelopmental disorder.
Tumor suppressor BAP1 nuclear import is governed by transportin-1.
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
BAP1 binds BAP1-interacting complex
BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1
Histone H2A is dubiquitinated by the PR-DUB complex
BAP1 disrupts the BRCA1:BARD1 heterodimer
BAP1 binds BRCA1:BARD1 heterodimer
BAP1/ASXL1 recruitment and activation for H2A deubiquitination.
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Loss of the tumor suppressor BAP1 causes myeloid transformation.