Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells.

ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.

human/SHLD2/SHLD2-uniprot.txt

human/SHLD2/SHLD2-hpa.xml

The shieldin complex mediates 53BP1-dependent DNA repair.