GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:21886777
Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility.
PMID:22610276
A novel COCH mutation associated with autosomal dominant nonsyndromic hearing loss disrupts the structural stability of the vWFA2 domain.
PMID:36399478
MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database.
PMID:9806553
Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction.
PMID:12843317
Subcellular localisation, secretion, and post-translational processing of normal cochlin, and of mutants causing the sensorineural deafness and vestibular disorder, DFNA9.
PMID:17926100
Cochlin isoforms and their interaction with CTL2 (SLC44A2) in the inner ear.
PMID:19013156
The second von Willebrand type A domain of cochlin has high affinity for type I, type II and type IV collagens.
PMID:21073934
Hearing and vestibular deficits in the Coch(-/-) null mouse model: comparison to the Coch(G88E/G88E) mouse and to DFNA9 hearing and balance disorder.
PMID:22159717
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
PMID:23684986
Cochlin produced by follicular dendritic cells promotes antibacterial innate immunity.
PMID:29449721
Bi-allelic inactivating variants in the COCH gene cause autosomal recessive prelingual hearing impairment.
PMID:30905438
Cleaved Cochlin Sequesters Pseudomonas aeruginosa and Activates Innate Immunity in the Inner Ear.
PMID:35901072
Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).
PMID:36511224
Construction of mouse cochlin mutants with different GAG-binding specificities and their use for immunohistochemistry.
PMID:40094079
Loss of Cochlin drives impairments in tendon structure and function.
PMID:41803274
A 62-aa core of the cochlin LCCL domain induces macrophage M1 polarization in vitro.
file:human/COCH/COCH-primary-excerpts.md
Selected original COCH migration-assay passages