Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity.
The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes.
Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy.
C. elegans screen identifies autophagy genes specific to multicellular organisms.
Insights on autophagosome-lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5.
Structure of the human autophagy factor EPG5 and the molecular basis of its conserved mode of interaction with Atg8-family proteins.